Some further evidence for partial agonist activity of labetalol.
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چکیده
منابع مشابه
Benzodiazepine Ro 15-1788: electrophysiological evidence for partial agonist activity.
The effects of diazepam and Ro 15-1788 were assessed upon responses of mouse spinal cord (SC) neurons in cell culture to the amino acid neurotransmitters 4-aminobutyric acid (GABA) and S-glutamic acid. Diazepam (100 nM) enhanced GABA responses by 65 +/- 3% (113 cells), while Ro 15-1788 (100 nM) failed to alter GABA responses but reduced their enhancement by diazepam. Higher Ro 15-1788 concentra...
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Further Evidence for Activity - Related Radial
The discovery of planets around several solar-like stars by means of high precision radial velocity (v r) measurements makes it important to explore sources of v r variations intrinsic to the stars themselves. Such studies guard against false planet detections, and can guide planet searches towards stars with low v r \noise" levels. We explore v r variations related to stellar activity { the ro...
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متن کاملTheory of partial agonist activity of steroid hormones
The different amounts of residual partial agonist activity (PAA) of antisteroids under assorted conditions have long been useful in clinical applications but remain largely unexplained. Not only does a given antagonist often afford unequal induction for multiple genes in the same cell but also the activity of the same antisteroid with the same gene changes with variations in concentration of nu...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1980
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1980.tb05849.x